The association between non-metropolitan residence and the risk of poo
r birth outcome in the United Stares was examined using the records of
11.06 million singleton births in the United States between 1985 and
1987. Rates of neonatal and post-neonatal death, low birth weight and
late prenatal care among non-metropolitan residents were compared to t
he rates among metropolitan residents. The association between residen
ce in a non-metropolitan area and the risk of poor birth outcome was a
ssessed in national and state level regression analyses. Residence in
a non-metropolitan county was not found to be associated with increase
d risk of low birth weight or neonatal mortality at the national level
or in most states, after controlling for several demographic and biol
ogical risk factors. Non-metropolitan residence was associated with gr
eater risk of post-neonatal mortality at the national level. Nonmetrop
olitan residence was strongly associated with late initiation of prena
tal care at both the national level and in a majority of the states. R
esidence in non-metropolitan areas does not appear to be associated wi
th higher risk of adverse birth outcome. Regionalization of perinatal
care and other changes in the rural health care system may have mitiga
ted the risk associated with residing in areas relatively isolated fro
m tertiary care. High levels of late prenatal care among non-metropoli
tan residents suggest a continuing problem of access to routine care f
or rural women and their infants that may be associated with higher le
vels of post-neonatal mortality and childhood morbidity. (C) 1997 Else
vier Science Ltd.