Problem solving learning: Applications in medicinal chemistry

This study describes the implementation of a didactic methodology in medici nal chemistry known as problem solving learning. Students were divided into groups of four to nine students predicted to have varying aptitudes in the se classes based on their performances in previous chemistry courses. Prior to coming to each class, students are required to read a specific portion of the class notes and answer the questions posed at the end of each readin g assignment. A problem set based on the designated reading is distributed to all students who then work in the small discussion groups. At the commen cement of the next class, answers to the problem set are presented by the i nstructor or alternatively by students from one or more of the groups. This approach is viewed positively by the students as a stimulating and challen ging way to understand medicinal chemistry.