S. Deehan et al., Intubation conditions and postoperative myalgia in outpatient dental surgery: A comparison of succinylcholine with mivacurium, ANAESTH I C, 28(2), 2000, pp. 146-150
Ninety-four patients undergoing elective outpatient third molar extraction
were recruited into a double-blind, randomized, prospective trial comparing
mivacurium (group hi) with succinylcholine (Group S) for conditions for en
dotracheal intubation and the occurrence of postoperative myalgia. Anaesthe
sia was induced with fentanyl 1 mu g.kg(-1) and propofol 2.5 mg.kg(-1) in a
ll patients, Group S patients were given gallamine 20 mg while group M pati
ents were given mivacurium 0.2 mg.kg(-1). Manual ventilation was commenced
and anaesthesia maintained with nitrous oxide 70% and isoflurane I to 2% in
oxygen. After two minutes, group S patients were given succinylcholine 1.5
mg.kg(-1) and group M patients 0.9% saline, Nasotracheal intubation was pe
rformed 30 seconds Infer: Intubating conditions iii group M were significan
tly better than those in group S (P<0.001), The incidence of postoperative
myalgia was 9.5% in group M and 26% in group S but this was not statistical
ly significant (P=0.09). We propose that mivacurium is a suitable neuromusc
ular blocker to use for endotracheal intubation in outpatient dental surger
y.