L. Magnani et al., Spectrophotometric measurement of antioxidant properties of flavones and flavonols against superoxide anion, ANALYT CHIM, 411(1-2), 2000, pp. 209-216
The antioxidant properties of 12 hydroxyflavones (including flavonols) and
eight methoxyflavones were evaluated using the pyrogallol UV-VIS spectropho
tometric method to generate superoxide anion. Pro- and antioxidant activity
depends of the flavone concentration in the medium. Results show that the
hydroxylation (on the C ring) of the 3- position (flavonols) enhanced antio
xidant properties more than methoxylation. A similar phenomenon is observed
for hydroxylation at the 2'-and 4'-positions (B ring). Hydroxylation or me
thoxylation on the 7- position (A ring), however, has a negative effect on
the radical scavenger activity. (C) 2000 Elsevier Science B.V. All rights r
eserved.