Examination of structural changes of polymeric amino acid-based surfactants on enantioselectivity: Effect of amino acid order, steric factors, and number and position of chiral centers

Citation
E. Billiot et Im. Warner, Examination of structural changes of polymeric amino acid-based surfactants on enantioselectivity: Effect of amino acid order, steric factors, and number and position of chiral centers, ANALYT CHEM, 72(8), 2000, pp. 1740-1748
Citations number
15
Categorie Soggetti
Chemistry & Analysis","Spectroscopy /Instrumentation/Analytical Sciences
Journal title
ANALYTICAL CHEMISTRY
ISSN journal
00032700 → ACNP
Volume
72
Issue
8
Year of publication
2000
Pages
1740 - 1748
Database
ISI
SICI code
0003-2700(20000415)72:8<1740:EOSCOP>2.0.ZU;2-7
Abstract
In this study, a large number of polymeric chiral surfactants were examined and their performances in terms of enantiomeric resolution compared for a variety of chiral analytes, The surfactants investigated in this study incl ude all possible dipeptide combinations of the L-form of alanine, valine, l eucine, and the achiral amino acid glycine (except glycine-glycine). Also i ncluded in this study were the single amino acid surfactants of alanine, va line, and leucine as well as the single chiral center dipeptide surfactant poly(sodium undecyl-L-leucine-beta-alanine) (poly L-SUL beta A). Several di fferent aspects of polymeric dipeptide surfactants, as they pertain to chir al separations, are examined. Some of the factors investigated in this repo rt include the effect of position and number of chiral centers, amino acid order, and steric effects.