The observed oxygen abundances in a number of irregular galaxies have been
compared with predictions of the closed-box model of chemical and photometr
ic evolution of galaxies. Oxygen is found to be deficient with respect to t
he predicted abundances. This is an indicator in favor of loss of heavy ele
ments via galactic winds or/and of infall of low-abundance gas onto the gal
axy.
The oxygen abundance deficiency observed within the optical edge of a galax
y cannot be explained by mixing with the gas envelope observed outside the
optical limit. We confirm the widespread idea that a significant part of th
e heavy elements is ejected by irregular galaxies in the intergalactic medi
um.