Molecular properties of the inositol (1,4,5) trisphosphate receptors from intracellular calcium stores

Authors
Murin, R Lehotsky, J Racay, P Fedorova, J Kaplan, P
Citation
R. Murin et al., Molecular properties of the inositol (1,4,5) trisphosphate receptors from intracellular calcium stores, BIOLOGIA, 54, 1999, pp. 35-39
Citations number
39
Categorie Soggetti
Biology
Journal title
BIOLOGIA
ISSN journal
00063088 → ACNP
Volume
54
Year of publication
1999
Supplement
6
Pages
35 - 39
Database
ISI
SICI code
0006-3088(1999)54:<35:MPOTI(>2.0.ZU;2-H
Abstract
The article briefly reviews recent published data on neuronal Ca2+ stores a nd their InsP(3) receptors. The InsP(3) receptor is a Ca2+ releasing channe l that allows Ca2+ release in response to the binding of InsP(3). Several g enes, which share extensive structural homology, encode the InsP(3) recepto r. The InsP(3) is modulated in a complex way by various cellular components . The regulation of InsP(3) is important in several aspects of cellular cal cium signalling.