M. Picquart et al., Low frequency vibrations and structural characterization of a murine IgG2amonoclonal antibody studied by Raman and IR spectroscopies, BIOPOLYMERS, 53(4), 2000, pp. 342-349
The Raman and ir spectra of a murine IgG2a monoclonal antibody molecule are
reported. In accordance with previous studies on immunoglobulins, the seco
ndary structure is predominantly of the beta-sheet type. The low frequency
region of the Raman spectrum was also analyzed in detail. A structured band
with two maxima near 43 a,ld 94 cm(-1) was observed This band has been att
ributed to vibrations of elastic body. The results are interpreted using a
simple elastic model. (C) 2000 John Wiley & Sons, Inc.