Human oesophageal adenocarcinoma cell lines JROECL 47 and JROECL 50 are admixtures of the human colon carcinoma cell line HCT 116

Authors
Wijnhoven, BPL Tilanus, MGJ Morris, AG Darnton, SJ Tilanus, HW Dinjens, WNM
Citation
Bpl. Wijnhoven et al., Human oesophageal adenocarcinoma cell lines JROECL 47 and JROECL 50 are admixtures of the human colon carcinoma cell line HCT 116, BR J CANC, 82(9), 2000, pp. 1510-1512
Citations number
16
Categorie Soggetti
Oncology,"Onconogenesis & Cancer Research
Journal title
BRITISH JOURNAL OF CANCER
ISSN journal
00070920 → ACNP
Volume
82
Issue
9
Year of publication
2000
Pages
1510 - 1512
Database
ISI
SICI code
0007-0920(200005)82:9<1510:HOACLJ>2.0.ZU;2-A
Abstract
In two recently described human oesophageal adenocarcinoma cell lines JROEC L 47 and JROECL 50, derived from one tumour, we detected identical E-cadher in and beta-catenin gene mutations as in colon carcinoma cell line HCT 116. We demonstrate by HLA-typing, mutation analysis and microsatellite analysi s that cell fines JROECL 47 and JROECL 50 are admixtures of the human colon adenocarcinoma cell line HCT 116. (C) 2000 Cancer Research Campaign.