Feasibility of targeted early detection for melanoma: a population-based screening study

The feasibility of targeted screening for cutaneous malignant melanoma in t he UK using a postal questionnaire and invitation to screening by a consult ant dermatologist was investigated in a population based cross-sectional su rvey. A total of 1600 people aged 25-69 years, stratified by the social dep rivation score of wards within one general practice, were randomly selected from a population of 8000.1227 (77%) returned the questionnaire and 896 (5 6%) attended the screening clinic. Uptake was lower for men (P < 0.001), th ose aged under 50 (P < 0.001), people from deprived areas (P < 0.001) and s kin types III and IV (men only, P < 0.001). Twenty per cent of women and 10 % of men felt nervous about attending the clinic, but only 4% were worried by the questionnaire. The level of agreement between the self- and dermatol ogist's assessments of risk factors was best for hair colour (Kappa = 0.67, sensitivity 73% and specificity 98%). People tended to under-report their level of risk. Over 95% knew about at least one major sign, but 54% reporte d incorrect signs of melanoma. Targeted screening for melanoma in the UK wi ll be hampered by difficulties in accurately identifying the target populat ion. Strategies to improve skin self-awareness rather than screening should be developed and evaluated. (C) 2000 Cancer Research Campaign.