To assess the role of scintigraphic evaluation of distal limb perfusio
n, the medical records and scintigraphic perfusion images of 17 animal
s (8 dogs, 2 cats, 2 calves, 4 birds and 1 ferret) with clinical signs
of distal limb ischemia were examined retrospectively. Images were ob
tained at 5 and 10 minutes following injection of Tc-99m-MDP, or Tc-99
m-DTPA. The initial scintigraphic diagnoses of 17 animals included com
plete ischemia (8/17), partially reduced perfusion (5/17), and normal
to increased perfusion (4/17), In 4 of the animals with partially redu
ced perfusion, follow-up scans indicated progression to complete ische
mia (1/4) or normal to increased perfusion (3/4), Nine of 17 animals h
ad a final scintigraphic diagnosis of complete distal limb ischemia, a
nd these animals were either euthanized (5/9) or had limb amputation (
4/9), A final diagnosis of complete ischemia was supported with either
repeat scanning (3/10), continued clinical observation (6/10) and/or
pathological examination (10/10), Clinical signs of ischemia resolved
in all (7/17) animals with increased or normal perfusion on their fina
l scan, Scintigraphy provided a safe and noninvasive assessment of dis
tal limb perfusion, which corresponded with clinical outcome.