Progress of the nucleic acid molecular "Light Switch"

The progress of nucleic acid molecular "Light Switch" and DNA was reviewed in this paper, which is obtained with ultraviolet absorption spectrum, fluo remetry, NMR, T-m and linear dicroism(LD), etc. The mechanism of fluorescen ce enhancement of molecular "Light Switch" by DNA and the charge transfer r eaction between Ru( II ) and Rh( II ) are reported. It also describes the a pplication of nucleic acid molecular "Light Switch" in sequence analysis, q uantitative analysis of DNA, determination of c(cm) and detection of solven t polarity. The possible development of the nucleic acid molecular "Light S witch" is addressed.