Outbreak of Pasteurella pneumotropica in a closed colony of STOCK-Cd28(tm1Mak) mice

Authors
Artwohl, JE Flynn, JC Bunte, RM Angen, O Herold, KC
Citation
Je. Artwohl et al., Outbreak of Pasteurella pneumotropica in a closed colony of STOCK-Cd28(tm1Mak) mice, CONT T LAB, 39(1), 2000, pp. 39-41
Citations number
21
Categorie Soggetti
Animal Sciences
Journal title
CONTEMPORARY TOPICS IN LABORATORY ANIMAL SCIENCE
ISSN journal
10600558 → ACNP
Volume
39
Issue
1
Year of publication
2000
Pages
39 - 41
Database
ISI
SICI code
1060-0558(200001)39:1<39:OOPPIA>2.0.ZU;2-T
Abstract
Fifteen mice with Pasteurella pneumotropica orbital abscesses were noted in mice that were homozygous for a targeted Cd28 gene mutation. Only one mous e heterozygous for the Cd28 mutation was affected. According to phenotypic reactions and 16S rDNA sequencing, the isolates were most similar to biotyp e Heyl, This article provides evidence for an immunologic basis of suscepti bility to P. pneumotropica infection.