Nucleic acids: theory and computer simulation, Y2K

Authors
Beveridge, DL McConnell, KJ
Citation
Dl. Beveridge et Kj. Mcconnell, Nucleic acids: theory and computer simulation, Y2K, CURR OP STR, 10(2), 2000, pp. 182-196
Citations number
160
Categorie Soggetti
Biochemistry & Biophysics
Journal title
CURRENT OPINION IN STRUCTURAL BIOLOGY
ISSN journal
0959440X → ACNP
Volume
10
Issue
2
Year of publication
2000
Pages
182 - 196
Database
ISI
SICI code
0959-440X(200004)10:2<182:NATACS>2.0.ZU;2-#
Abstract
Molecular dynamics simulations on DNA and RNA that include solvent are now being performed under realistic environmental conditions of water activity and salt. improvements to force-fields and treatments of long-range interac tions have significantly increased the reliability of simulations. New stud ies of sequence effects, axis bending, solvation and conformational transit ions have appeared.