Ataxic form of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP)

We reported a 64-year-old male with an eight-month history of Salt disturba nce and sensory impairment. The patient initially noticed unsteadiness of g ait and numbness in his feet, and these symptoms progressed until he was un able to walk without assistance five months later. Vibratory sensation and position sense were markedly diminished, and deep tendon reflexes were abse nt in all extremities. Motor conduction velocities were slow with prolonged distal latencies, and sensory nerve action potentials (SNAP) were trot eli cited. Sural nerve biopsy revealed a mild loss of myelinated fibres and seg mental demyelination. Cerebrospinal fluid showed normal cell count with pro tein 526 mg/dL. Anti-GM1, anti-GM2 and anti-GA1 antibodies in serum were po sitive. We diagnosed chronic inflammatory demyelinating polyradiculoneuropa thy (CIDP) presenting ataxia. Steroid therapy provided immediate improvemen t of symptoms and signs. This case suggests that CIDP should be considered as one of the potential causes of ataxic neuropathy.