Paroxysmal dystonia induced by exercise and acetazolamide

We report a case of a 40-year-old woman with dystonic attacks precipitated by slight exercise. Episodes lasted 2-5 min and were not precipitated by su dden movements or by being startled, drinking alcohol, coffee or tea, or by stress. Secondary dystonia was ruled out and brain magnetic resonance imag ing (MRI) was unremarkable, Routine and video electroencephalogram (EEG) du ring and between attacks were normal. Acetazolamide greatly worsened her co ndition, whereas gabapentin [1-(aminomethyl) cyclohexaneacetic acid] treatm ent markedly reduced the frequency and severity of the episodes.