Marker-assisted selection using ridge regression

Citation
Jc. Whittaker et al., Marker-assisted selection using ridge regression, GENET RES, 75(2), 2000, pp. 249-252
Citations number
17
Categorie Soggetti
Molecular Biology & Genetics
Journal title
GENETICAL RESEARCH
ISSN journal
00166723 → ACNP
Volume
75
Issue
2
Year of publication
2000
Pages
249 - 252
Database
ISI
SICI code
0016-6723(200004)75:2<249:MSURR>2.0.ZU;2-H
Abstract
In crosses between inbred lines, linear regression can be used to estimate the correlation of markers with a trait of interest; these marker effects t hen allow marker assisted selection (MAS) for quantitative traits. Usually a subset of markers to include in the model must be selected: no completely satisfactory method of doing this exists. We show that replacing this sele ction of markers by ridge regression can improve the mean response to selec tion and reduce the variability of selection response.