Ethoxyresorufin O-deethylase (EROD) activity in the liver of dab (Limanda limanda L.) and flounder (Platichthys flesus L.) from the German Bight. EROD expression and tissue contamination

Authors
von Westernhagen, H Kruner, G Broeg, K
Citation
H. Von Westernhagen et al., Ethoxyresorufin O-deethylase (EROD) activity in the liver of dab (Limanda limanda L.) and flounder (Platichthys flesus L.) from the German Bight. EROD expression and tissue contamination, HELG MAR R, 53(3-4), 1999, pp. 244-249
Citations number
36
Categorie Soggetti
Aquatic Sciences
Journal title
HELGOLAND MARINE RESEARCH
ISSN journal
1438387X → ACNP
Volume
53
Issue
3-4
Year of publication
1999
Pages
244 - 249
Database
ISI
SICI code
1438-387X(1999)53:3-4<244:EO(AIT>2.0.ZU;2-0
Abstract
Ethoxyresorufin O-deethylase (EROD) activity was measured in the liver of d ab (Limanda (limanda) and Flounder (Platichthys flesus) from the German Eig ht (southern North Sea) and compared with muscle and liver polychlorinated biphenyl (PCB) concentrations in an attempt to relate EROD activity to PCB body burden. Tn none of the different datasets (species-, tissue- or matrix -dependent) was a significant (P<0.05) correlation between PCB tissue conta mination and EROD activity found. Yet EROD activity was significantly corre lated with polycyclic aromatic hydrocarbons (PAH) levels (phenanthrene, flu oranthene, pyrene) in muscle tissue, indicating a possible dependence of ER OD expression on other ubiquitous organic contaminants, thus making it a su itable biomarker for general pollution.