Oral findings in three different groups of immunocompromised patients

The objective of this study was to determine the frequency of oral, dental and periodontal findings in three different groups of immunocompromised pat ients and in a healthy control group, to evaluate whether there is a correl ation between manifestations of disease and immunologic parameters. The sur vey included 46 patients with a diagnosis of systemic lupus erythematosus, 48 heart transplant recipients, and 53 adult patients suffering from acute leukemias. Fifty matched healthy subjects were used as a control group. Eac h patient had to answer questions on medical and dental health and underwen t a thorough oral, dental and serological investigation. Oral mucosal lesio ns were found in nearly half of all immunocompromised patients (49.6%), but in only 26% of control patients. No significant associations were found be tween different types of oral lesions and the underlying cause of immunosup pression. Leukemia patients showed age-unrelated higher scores in periodont al indices (P<0.05). Laboratory parameters failed to be significant in the assessment of oral health.