Mercury exposure does not elevate systolic blood pressure in normotensive rats

Authors
Takahashi, H Nomiyama, H Nomiyama, K
Citation
H. Takahashi et al., Mercury exposure does not elevate systolic blood pressure in normotensive rats, J TR EL EXP, 13(2), 2000, pp. 239-247
Citations number
23
Categorie Soggetti
Endocrinology, Nutrition & Metabolism
Journal title
JOURNAL OF TRACE ELEMENTS IN EXPERIMENTAL MEDICINE
ISSN journal
0896548X → ACNP
Volume
13
Issue
2
Year of publication
2000
Pages
239 - 247
Database
ISI
SICI code
0896-548X(2000)13:2<239:MEDNES>2.0.ZU;2-Y
Abstract
Wistar-Kyoto rats are the original normotensive strain of the spontaneously hypertensive rat (SHR). Fifty male Wistar-Kyoto rats were fed 15 g/day of pelleted food containing mercuric chloride (HgCl2) at dose levels of 0, 1, 3, 10, or 30 mu g/g over a period of 21 weeks. No dose-related difference i n blood pressure was observed in normotensive rats of the Wistar-Kyoto stra in fed mercuric chloride. J. Trace Elem. Exp. Med. 13:239-247, 2000. (C) 20 00 Wiley-Liss, Inc.