Gb. Anderson et al., CLINICAL EFFECTS OF CHLORHEXIDINE MOUTHWASHES ON PATIENTS UNDERGOING ORTHODONTIC TREATMENT, American journal of orthodontics and dentofacial orthopedics, 111(6), 1997, pp. 606-612
This study compared the short-term clinical effect of 0.12% chlorhexid
ine gluconate and placebo mouthrinses in 30 adolescents (ages 11 to 15
) undergoing orthodontic treatment. Subjects were randomized into expe
rimental (CHX) and control (C) groups. Baseline values were recorded 1
0 days after prophylaxis and included Plaque Index (PI), Gingival Inde
x (GI), Rentention Index (RI), Discoloration Index (DI), and probing d
epths (PD). Both groups (CHX and C) received soft toothbrushes with in
structions to brush twice daily, as well as the CHX and placebo mouthr
inses, respectively, with oral and written instructions for rinsing tw
ice daily with 15 ml for 30 seconds. Reevaluations were performed 1, 2
, and 3 months after baseline, except for the DI and PD, which were on
ly assessed at 3 months. The Student's t test and the paired t test we
re used to analyze the data at the P < 0.05 level of significance. No
differences between groups were seen at baseline for any of the parame
ters. At 30 days, there was a significant difference for the RI betwee
n CHX (0.15 +/- 0.16; mean +/- SD) and C (0.05 +/- 0.06) at the mesial
buccal, and for CHX (0.07 +/- 0.10) and C (0.02 +/- 0.05) at the midb
uccal. The 60-day evaluation showed similar results. At 90 days, lower
PI were observed in the CHX group at the distal buccal (0.38 +/- 0.19
), midbuccal (0.22 +/- 0.17), and mesial buccal (0.47 +/- 0.22) sites
as compared with the C group (0.97 +/- 0.38, 0.83 +/- 0.40, and 0.95 /- 0.43, respectively). A similar trend was noted with the GI, as the
lower values were related to the CHX group. The changes of the PI and
GI, at 30, 60, and 90 days, as analyzed by the paired t test, were sta
tistically significant in the case of the experimental group, as the c
hanges in the means were a reflection of significantly lower scores ob
served in the experimental group. After 3 months, the DI showed higher
scores in the experimental group as compared with the control, but th
ey were not statistically significant. Deeper PD were detected in the
C group at 90 days, and they were statistically significant, except fo
r the midlingual site. The RI did not show significant differences at
90 days, but higher values were recorded in the CHX group. The data in
dicate that the use of the CHX, in addition to regular oral hygiene ha
bits, was effective in reducing plaque and gingivitis in adolescents u
ndergoing orthodontic treatment.