THE FEET IN CROUZON-SYNDROME

Eighteen patients with Crouzon syndrome were evaluated for anomalies o f the feet. Clinical examination was unremarkable in all cases. Radiog raphs were evaluated by a radiologist with an interest in skeletal dys plasia, along with the craniofacial team. A range of radiographic anom alies was seen, with the phalanges, metacarpals, and tarsals all displ aying anomalies. Only three cases had radiographically normal feet. Th ese findings suggest that the effects on the feet, which, although sub tle and not well described in the literature, are notable. Feet anomal ies also occur with the other complex craniosynostosis syndromes resul ting from mutations of fibroblastic growth factor receptor 2 molecule, such as those of Apert, Pfeiffer, and Jackson-Weiss syndromes.