W. Szweda et al., The possibilities of Aujeszky's disease virus elimination from pig populations using "vaccination-eradication programme", MED WETER, 56(3), 2000, pp. 177-181
The great progress achieved in recent ears in molecular biology and genetic
engineering disciplines enabled the creation of Aujeszky's disease (AD) vi
rus (SHV-1) deletion mutants, which establish a base for the elaboration of
deletion (marker) vaccines. These vaccines together with appropriate serol
ogical tests (ELISA) enable the realization of a vaccination-eradication pr
ogramme that gives real chances to eliminate SHV-1 from infected farms (reg
ions, countries). The objective of the study was to introduce and evaluate
the possibilities of SHV-1 elimination from pig populations in two highly i
nfected pig farms in the Warmia and Masuria province in Poland. Pig vaccina
tions were done using deleted, gE- and TK-negative, live attenuated Nobi -
Porvac Aujeszky Live Begonia vaccine (at present Porcilis Begonia) produced
by Intervet Int., Holland. Reproductive pigs were vaccinated twice 3 weeks
apart and then every 4 months at the same time. Replacement gilts were vac
cinated twice before service and replacement boars twice in the quarantine
period. Piglets born to vaccinated dams were vaccinated at 10-12 and 14-16
weeks of age. Observations of postvaccinal adverse effects and control of t
he epizootic situation in both herds were conducted.
Clinical and epizootiological studies revealed neither local nor general ad
verse effects in pigs of various age groups. In spite of high SHV-1 infecti
on levels no clinical signs of AD during vaccination - eradication programm
e in both herds were observed. This proved innocuity and good efficacy of P
orcilis Begonia vaccine.
The stages of implementing the vaccination-eradication programme in pig her
ds, as well as the necessity of a quick introduction of a complex AD eradic
ation programme in Poland according to the general tendency in the EU were
also presented in the paper.