Synthesis of functionalized oxazolines and oxazoles with DAST and deoxo-fluor

Authors
Phillips, AJ Uto, Y Wipf, P Reno, MJ Williams, DR
Citation
Aj. Phillips et al., Synthesis of functionalized oxazolines and oxazoles with DAST and deoxo-fluor, ORG LETT, 2(8), 2000, pp. 1165-1168
Citations number
30
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
ORGANIC LETTERS
ISSN journal
15237060 → ACNP
Volume
2
Issue
8
Year of publication
2000
Pages
1165 - 1168
Database
ISI
SICI code
1523-7060(20000420)2:8<1165:SOFOAO>2.0.ZU;2-N
Abstract
A mild and highly efficient cyclization of beta-hydroxy amides to oxazoline s is described using DAST and Deoxo-Fluor reagents. A one-pot protocol for the synthesis of oxazoles from beta-hydroxy amides is also presented.