Transient nonketotic hyperglycinemia in an asphyxiated patient with pyridoxine-dependent seizures

Authors
Maeda, T Inutsuka, M Goto, K Izumi, T
Citation
T. Maeda et al., Transient nonketotic hyperglycinemia in an asphyxiated patient with pyridoxine-dependent seizures, PED NEUROL, 22(3), 2000, pp. 225-227
Citations number
13
Categorie Soggetti
Pediatrics,"Medical Research General Topics
Journal title
PEDIATRIC NEUROLOGY
ISSN journal
08878994 → ACNP
Volume
22
Issue
3
Year of publication
2000
Pages
225 - 227
Database
ISI
SICI code
0887-8994(200003)22:3<225:TNHIAA>2.0.ZU;2-0
Abstract
An asphyxiated neonate with pyridoxine-dependent seizures and associated tr ansient nonketotic hyperglycinemia is reported. Frequent seizures and their resultant hypoxic-ischemic insult may have led to the elevation of the cer ebrospinal fluid glycine level in this patient. Early diagnosis and treatme nt of pyridosine-dependent seizures is essential for an improved neurologic outcome. (C) 2000 by Elsevier Science Inc. All rights reserved.