Cycloaromatization and DNA cleavage of novel non-conjugated aromatic enetetrayne systems

Authors
Ueda, I Miyawaki, K Sugane, T Sakurai, Y Wada, Y Futai, M
Citation
I. Ueda et al., Cycloaromatization and DNA cleavage of novel non-conjugated aromatic enetetrayne systems, PHARMAZIE, 55(3), 2000, pp. 192-195
Citations number
11
Categorie Soggetti
Pharmacology & Toxicology
Journal title
PHARMAZIE
ISSN journal
00317144 → ACNP
Volume
55
Issue
3
Year of publication
2000
Pages
192 - 195
Database
ISI
SICI code
0031-7144(200003)55:3<192:CADCON>2.0.ZU;2-W
Abstract
The novel, non-conjugated aromatic enetetrayne (2) underwent thermal cycloa romatization reaction to give polyphenylene derivative 6, forming a methyl cation as an active intermediate, and showed DNA-cleaving activity.