Simulating inbreeding depression through the mutation accumulation theory

Authors
Sousa, AO de Oliveira, SM Bernardes, AT
Citation
Ao. Sousa et al., Simulating inbreeding depression through the mutation accumulation theory, PHYSICA A, 278(3-4), 2000, pp. 563-570
Citations number
20
Categorie Soggetti
Physics
Journal title
PHYSICA A
ISSN journal
03784371 → ACNP
Volume
278
Issue
3-4
Year of publication
2000
Pages
563 - 570
Database
ISI
SICI code
0378-4371(20000415)278:3-4<563:SIDTTM>2.0.ZU;2-Q
Abstract
Using the Penna model for biological aging, which is based on the mutation accumulation theory, we show that the number of homozygous loci correspondi ng to deleterious mutations is higher in small populations than in large on es. This decrease of heterozygosity may drive small populations to extincti on even when no drastic change of the environment occurs. (C) 2000 Elsevier Science B.V. All rights reserved.