2,3-Bis-O-(tert-butyldimethylsilyl)-5,6-O-isopropylidene-D-glucono-1,4-lact
one has been easily prepared from commercially available starting material
and its activity investigated. Based on the lactone functionality, this com
pound can proceed via nucleophilic addition, reduction, and hydrolysis to g
enerate various highly functionalized molecules. (C) 2000 Elsevier Science
Ltd. All rights reserved.