Kj. Elgie et al., Application of combinatorial techniques in the synthesis of unsymmetrically substituted 5,15-diphenylporphyrins, TETRAHEDR L, 41(15), 2000, pp. 2753-2757
Combinatorial techniques, both solid and solution phase, have been applied
to the synthesis of unsymmetrically substituted 5,15-diphenylporphyrins. 5-
(4-Hydroxyphenyl)-15-pentafluorophenylporphyrin can be loaded onto solid su
pports and substituted on the pentafluorophenyl ring with thiols. Diversity
is then expanded by cleavage and solution phase substitution of the second
phenyl ring using a solid supported base. (C) 2000 Elsevier Science Ltd. A
ll rights reserved.