Intraoperative hyperpyrexia in osteogenesis imperfecta patients.

The aim of this study was to evaluate the influence of different types of a nesthesia upon the intra- and postoperative body temperature in osteogenesi s imperfecta patients. The development of an intraoperative hyperpyrexia of unknown origin is a typical phenomenon in patients with osteogenesis imper fecta. Body temperatures of up to 40 degrees C are known to complicate the operation. Therefore, in a retrospective study, the pre- intra- and postope rative body temperature curves of 45 operations under different anaesthesia s were measured. Group A underwent a common balanced anaesthesia with the v olatile anaesthetic Enfluran in combination with Fentanyl, while group B wa s operated on under total intravenous anaesthesia (TIVA) with Propofol and Alfentanil. The preoperative temperatures were not different in the two gro ups. The intraoperative curves showed a constant body core temperature or e ven an increase under Enfluran, while the temperature always decreased unde r TIVA. This could be confirmed by intraindividual studies in 5 patients.