Aims. To examine the longitudinal association between cannabis use and ment
al health. Design. Information concerning cannabis use and mental health fr
om 15 to 21 years was available for a large sample of individuals as pan of
a longitudinal study from childhood to adulthood Participants. Participant
s were enrolled in the Dunedin Multidisciplinary Health and Development Stu
dy, a research programme on the health, development and behaviour of a larg
e group of New Zealanders born between I April 1972 and 31 March 1973. Meas
urements. Cannabis use and identification of mental disorder was based upon
self-report as pan of a general assessment of mental health using a standa
rd diagnostic interview. Daily smoking and alcohol use at age 15 were asses
sed by self-report. Indices of family socio-economic status, family climate
and parent-child interaction were formed using information gathered from p
arent report and behavioural observations over early childhood. Childhood b
ehaviour problems were assessed by parent and reacher report. Attachment to
parents was assessed in adolescence. Findings. Cross-sectional association
s between cannabis use and mental disorder were significant at all three ag
es. Both outcome variables shared similar pathways of low socio-economic st
atus and history of behaviour problems in childhood, and low parental attac
hment in adolescence. Mental disorder at age 15 led to a small but signific
antly elevated risk of cannabis use at age 18; by contrast, cannabis use at
age 18 elevated the risk of mental disorder at age 21. The latter associat
ion reflected the extent to which cannabis dependence and other externalizi
ng disorders at age 21 were predicted by earlier level of involvement with
cannabis. Conclusions. The findings suggest that the primary causal directi
on leads from mental disorder to cannabis use among adolescents and the rev
erse in early adulthood. Both alcohol use and cigarette smoking had indepen
dent associations with later mental health disorder.