Micromanipulation by microrobots has become an issue of primary importance
in industry and biomedicine, since human manual capabilities are restricted
to certain tolerances. The manipulation of biological cells or the assembl
y of a microsystem composed of several microcomponents are good examples. A
n automated microrobot-based micromanipulation desktop station has been dev
eloped at the University of Karlsruhe. The process of assembly takes place
in the field of view of a light optical microscope. This paper focuses on m
otion control problems of the piezo-driven microrobots employed by the stat
ion. The ability to adapt itself to the process requirements is of great im
portance for micromanipulation robots. They must be able to operate in a pa
rtially defined environment and to ensure reasonable behavior in unpredicte
d situations. A neural control concept based on a reference model is propos
ed as a solution. It is shown that the neural controller is able to learn t
he desired behavior. It considerably outperforms an analytically designed l
inear controller in the real environment.