Geographic distribution of a large mobile element that transfers ampicillin and vancomycin resistance between Enterococcus faecium strains

Authors
Hanrahan, J Hoyen, C Rice, LB
Citation
J. Hanrahan et al., Geographic distribution of a large mobile element that transfers ampicillin and vancomycin resistance between Enterococcus faecium strains, ANTIM AG CH, 44(5), 2000, pp. 1349-1351
Citations number
14
Categorie Soggetti
Microbiology
Journal title
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
ISSN journal
00664804 → ACNP
Volume
44
Issue
5
Year of publication
2000
Pages
1349 - 1351
Database
ISI
SICI code
0066-4804(200005)44:5<1349:GDOALM>2.0.ZU;2-U
Abstract
In several clonally unrelated VanB-type vancomycin-resistant Enterococcus f aecium strains, we demonstrated a common physical relationship between pbp5 and Tn5382 as well as common mutations within pbp5. The majority of these strains transferred vancomycin and ampicillin resistance to E. faecium in v itro, suggesting the dissemination of similar transferable pbp5-vanB-contai ning mobile elements throughout the United States.