Analysis of salbutamol and related impurities by derivative spectrometry

Authors
Aboul-Enein, HY Surmeian, M
Citation
Hy. Aboul-enein et M. Surmeian, Analysis of salbutamol and related impurities by derivative spectrometry, ARCH PHARM, 333(4), 2000, pp. 75-78
Citations number
16
Categorie Soggetti
Pharmacology & Toxicology
Journal title
ARCHIV DER PHARMAZIE
ISSN journal
03656233 → ACNP
Volume
333
Issue
4
Year of publication
2000
Pages
75 - 78
Database
ISI
SICI code
0365-6233(200004)333:4<75:AOSARI>2.0.ZU;2-1
Abstract
Ultraviolet derivative spectrometry has been proposed for the analysis of s albutamol and related impurities. The assay of salbutamol aldehyde, 5-formy l-saligenin, and salbutamol ketone was performed in sodium hydroxide 0.1 mo l/l solutions, using first and second derivative spectra. The method has be en applied for the assay of related impurities of commercial samples of sal butamol sulfate.