Involvement of the entire spinal cord and medulla oblongata in acute catastrophic-onset transverse myelitis in SLE

A 30-year-old Caucasian male with systemic lupus erythematosus suffered acu te catastrophic-onset transverse myelitis. Two years earlier aseptic mening itis, another rare CNS lupus manifestation, had been diagnosed. MRI showed involvement of the medulla oblongata and the entire spinal cord. Therapy wi th intravenous high-dose methylprednisolone and intravenous cyclophosphamid e is discussed.