Are the biologic and clinical effects of the COX-2-specific inhibitors an advance compared with the effects of traditional NSAIDs?

Authors
Simon, LS
Citation
Ls. Simon, Are the biologic and clinical effects of the COX-2-specific inhibitors an advance compared with the effects of traditional NSAIDs?, CURR OP RH, 12(3), 2000, pp. 163-170
Citations number
67
Categorie Soggetti
Rheumatology
Journal title
CURRENT OPINION IN RHEUMATOLOGY
ISSN journal
10408711 → ACNP
Volume
12
Issue
3
Year of publication
2000
Pages
163 - 170
Database
ISI
SICI code
1040-8711(200005)12:3<163:ATBACE>2.0.ZU;2-8
Abstract
This has been an unusual year for the accumulation of evidence regarding th e clinical effects of inhibition of cyclooxygenase (COX)-1 and COX-2, This article reviews the available data regarding the clinical effects of the ne w COX-2-specific inhibitors, and speculates about the importance of the dat a as they relate to the treatment of patients with chronic pain and/or infl ammation. Curr Opin Rheumaiol 2000, 12:163-170 (C) 2000 Lippincott Williams & Wilkins, Inc.