Radical excision of multifocal anal intraepithelial neoplasia - Report of a case

PURPOSE: The aim of this study was to describe the technique of radical exc ision of multifocal anal intraepithelial neoplasia and discuss controversia l issues surrounding the management of this condition. METHOD: We describe the case of a 31-year-old female with previous vulval warts, vulval squamou s carcinoma, and recent immunosuppression who had widespread anal intraepit helial neoplasia excised, and the resulting defect was split-skin grafted, including the anal canal. RESULTS: Excision and split-skin grafting was suc cessful in removing the disease and left a satisfactory cosmetic and functi onal result. CONCLUSION: Diffuse, high-grade, anal intraepithelial neoplasi a is rare. Excision of these lesions remains controversial but may be the b eat option.