Evidence of endothelium involvement in the pathophysiology of hydrops fetalis?

Authors
De Groot, CJM Oepkes, D Egberts, J Kanhai, HHH
Citation
Cjm. De Groot et al., Evidence of endothelium involvement in the pathophysiology of hydrops fetalis?, EAR HUM DEV, 57(3), 2000, pp. 205-209
Citations number
4
Categorie Soggetti
Pediatrics
Journal title
EARLY HUMAN DEVELOPMENT
ISSN journal
03783782 → ACNP
Volume
57
Issue
3
Year of publication
2000
Pages
205 - 209
Database
ISI
SICI code
0378-3782(200003)57:3<205:EOEIIT>2.0.ZU;2-E
Abstract
A fetus with signs of hydrops is at high risk of intrauterine death. The pa thophysiology of hydrops fetalis is still unclear. We found decreased conce ntrations of cyclic guanosine monophosphate in fetal plasma of alloimmunize d pregnancies complicated by hydrops fetalis, which might suggest reduced n itric oxide production due to injury of fetal vascular endothelial cells. ( C) 2000 Elsevier Science ireland Ltd. All rights reserved.