Vibrio cholerae O139 in Calcutta, 1992-1998: Incidence, antibiograms, and genotypes

Citation
A. Basu et al., Vibrio cholerae O139 in Calcutta, 1992-1998: Incidence, antibiograms, and genotypes, EM INFECT D, 6(2), 2000, pp. 139-147
Citations number
28
Categorie Soggetti
Clinical Immunolgy & Infectious Disease
Journal title
EMERGING INFECTIOUS DISEASES
ISSN journal
10806040 → ACNP
Volume
6
Issue
2
Year of publication
2000
Pages
139 - 147
Database
ISI
SICI code
1080-6040(200003/04)6:2<139:VCOIC1>2.0.ZU;2-C
Abstract
We report results of surveillance for cholera caused by Vibrio cholerae O13 9 from September 1992, when it was first identified, to December 1998. V. c holerae O139 dominated as the causative agent of cholera in Calcutta during 1992-93 and 1996-97, while the O1 strains dominated during the rest of the period. Dramatic shifts in patterns of resistance to cotrimoxazole, neomyc in, and streptomycin were observed. Molecular epidemiologic studies showed clonal diversity among the O139 strains and continuous emergence of new epi demic clones, reflected by changes in the structure, organization, and loca tion of the CTX prophages in the V. cholerae O139 chromosome.