Sin Nombre virus (SNV) Ig isotype antibody response during acute and convalescent phases of hantavirus pulmonary syndrome

Authors
Bostik, P Winter, J Ksiazek, TG Rollin, PE Villinger, F Zaki, SR Peters, CJ Ansari, AA
Citation
P. Bostik et al., Sin Nombre virus (SNV) Ig isotype antibody response during acute and convalescent phases of hantavirus pulmonary syndrome, EM INFECT D, 6(2), 2000, pp. 184-188
Citations number
16
Categorie Soggetti
Clinical Immunolgy & Infectious Disease
Journal title
EMERGING INFECTIOUS DISEASES
ISSN journal
10806040 → ACNP
Volume
6
Issue
2
Year of publication
2000
Pages
184 - 188
Database
ISI
SICI code
1080-6040(200003/04)6:2<184:SNV(II>2.0.ZU;2-2
Abstract
Serum samples from 22 hantavirus pulmonary syndrome (HPS) patients were tes ted for Sin Nombre virus (SNV)-reactive antibodies. In the acute phase of H PS, 100% and 67% of the samples tested positive for SNV-specific immunoglob ulin (Ig) M and IgA, respectively. Among the virus-specific IgG antibodies, the most prevalent were IgG3 (in 97% of samples), followed by IgG1 (70%), IgG2 (30%), and IgG4 (3%).