Pg. Luepke et al., A CLINICAL-EVALUATION OF A BIORESORBABLE BARRIER WITH AND WITHOUT DECALCIFIED FREEZE-DRIED BONE ALLOGRAFT IN THE TREATMENT OF MOLAR FURCATIONS, Journal of clinical periodontology, 24(6), 1997, pp. 440-446
This study evaluated a bioresorbable barrier with and without decalcif
ied Freeze-dried bone allograft (DFDBA) in the treatment of human mola
r furcations. 14 subjects with paired class II mandibular molar furcat
ion defects participated in the study (8 male and 6 female), The class
-II furcation defects were randomly treated with either the resorbable
barrier alone or resorbable barrier in combination with decalcified f
reeze-dried bone allograft (DFDBA). Gingival recession, probing depth,
clinical attachment, and bone fill were measured. 6 months post-treat
ment measurements were repeated and each site was surgically re-entere
d. When the resorbable barrier alone was compared to resorbable barrie
r in combination with DFDBA, probing depth reduction was significantly
(p<0,01) in favor of the combination therapy. Vertical bone gain was
significant with the combination treatment demonstrating more bone fil
l (p<0,02). Smoking was also a variable examined in this study, When c
ompared to smokers, nonsmokers for both treatment groups revealed grea
ter probing depth reduction, vertical bone gain, and horizontal bone g
ain, Within the non-smoking group, probing depth reduction was also si
gnificantly higher for the resorbable barrier and DFDBA group than the
resorbable alone group (p<0.02), These results illustrate that the pr
obing depth reduction is better in the non-smoker and the best in the
non-smoker with the combination therapy of resorbable barrier and DFDB
A than with resorbable barrier alone.