HIV-1 co-receptor CCR5 and CCR2 mutations among Greeks

The frequency of CCR5 and CCR2 alleles in human immunodeficiency virus (HIV )-positive and HIV-negative populations of Northern Greece was investigated . The frequency of the CCR5 Delta 32 allele among the HIV-negative subjects was 0.052, while it was approximately twofold lower among the seropositive s, suggesting that the heterozygous genotype confers a partial resistance t o the HIV infection. No significant difference in CCR2 allele frequency bet ween the two groups was observed. (C) 2000 Federation of European Microbiol ogical Societies. Published by Elsevier Science B.V. All rights reserved.