Single-molecule detection in solution: a new tool for analytical chemistry

Authors
Zander, C
Citation
C. Zander, Single-molecule detection in solution: a new tool for analytical chemistry, FRESEN J AN, 366(6-7), 2000, pp. 745-751
Citations number
79
Categorie Soggetti
Spectroscopy /Instrumentation/Analytical Sciences
Journal title
FRESENIUS JOURNAL OF ANALYTICAL CHEMISTRY
ISSN journal
09370633 → ACNP
Volume
366
Issue
6-7
Year of publication
2000
Pages
745 - 751
Database
ISI
SICI code
0937-0633(200003/04)366:6-7<745:SDISAN>2.0.ZU;2-8
Abstract
Single-molecule detection (SMD) is becoming more and more popular in the sc ientific community and is on the threshold to become a technique for labora tory use. Therefore, conceivable applications as well as optimized conditio ns for SMD will be discussed. To point out the possibilities of SMD, the si gnal-to-background ratio and the detection efficiency, in combination with the probability of misclassification, will be contemplated.