Characterization of ferrochelatase (hemH) mutations in Haemophilus influenzae

Authors
Schlor, S Herbert, M Rodenburg, M Blass, J Reidl, J
Citation
S. Schlor et al., Characterization of ferrochelatase (hemH) mutations in Haemophilus influenzae, INFEC IMMUN, 68(5), 2000, pp. 3007-3009
Citations number
22
Categorie Soggetti
Immunology
Journal title
INFECTION AND IMMUNITY
ISSN journal
00199567 → ACNP
Volume
68
Issue
5
Year of publication
2000
Pages
3007 - 3009
Database
ISI
SICI code
0019-9567(200005)68:5<3007:COF(MI>2.0.ZU;2-F
Abstract
Haemophilus influenzae lacks most of the biosynthetic enzymes for hemin syn thesis. However, the organism has retained ferrochelatase activity, which w e identified to be encoded by a hemN-homologous gene. In this report we cha racterize the growth physiology conferred by hemN mutations under infection and laboratory conditions.