Eight- and 16-membered cyanuric-sulfanuric ring systems: C2N4S2 -> C2N3S ring contraction

Eight- and 16-membered cyanuric-sulfanuric ring systems of the type Ar2C2N4 S2(O)(2)Ar'(2) (3a, Ar = 4-BrC6H4, Ar' = Ph; 3b, Ar = 4-CF3C6H4, Ar' = Ph; 3c, Ar' = 4-CF3C6H4, Ar' = 4-CH3C6H4) and Ar4C4N8S4(O)(4)Ar'(4) (4b, Ar = 4 -CF3C6H4, Ar' = Ph; 4c, Ar' = 4-CH3C6H4, Ar' = Ph; 4d, Ar = 4-CF3C6H4, Ar' = 4-CH3C6H4), respectively, were prepared in good yields by the reaction of the corresponding sulfur(IV) systems with m-chloroperbenzoic acid. The X-r ay structures of 3b, 3c.C7H14, 4b.CH2Cl2, 4c, and the S(IV) system Ar4C4N8S 4Ar'(4) (2C, Ar = 4-CH3C6H4, Ar' = Ph) were determined. Upon oxidation the two oxygen atoms in 3b and 3C.C7H14 adopt endo positions leading to a twist boat conformation for the C2N4S2 ring. The 16-membered C4N8S4 rings in 4b and 4c retain a cradle conformation upon oxidation. The S-N bond distances are ca. 0.06 Angstrom shorter in all the S(VI) systems compared to those in the corresponding S(TV) rings. The thermolysis of 3b at ca. 220 degrees C occurs primarily via loss of a sulfanuric group, NS(O)Ph, to give the six-m embered ring (4-CF3C6H4)(2)C2N3S(O)Ph (6). The structure of 6 was confirmed by X-ray crystallography. Crystal data: 2c, triclinic, space group P (1) o ver bar with a = 13.917(2) Angstrom, b = 15.610(4) Angstrom, c = 13.491(3) Angstrom, alpha = 95.77(2)degrees, beta = 114.82(1)degrees, gamma = 76.21(2 )degrees, V = 2583(1) Angstrom(3), and Z = 2; 3b, monoclinic, space group P 2(1)/a with a = 7.316(2) Angstrom, b = 29.508(5) Angstrom, c = 12.910(2) An gstrom, beta = 101.30(2)degrees, V = 2733(1) Angstrom(3), and Z = 4; 3c.C7H 14, triclinic, space group P (1) over bar with a = 12.849(4) Angstrom, b = 12.&65(4) Angstrom, c = 12.610(7) Angstrom, alpha = 110.61(3)degrees, beta = 105.77(3)degrees, gamma = 62.77(2)degrees, V = 1719(1) Angstrom(3), and Z = 2; 4b.CH2Cl2, triclinic, space group P (1) over bar with a = 12.647(3) A ngstrom, b = 19.137(3) Angstrom, c = 12.550(2) Angstrom, alpha = 105.765(11 )degrees, beta = 93.610(15)degrees, gamma = 88.877(16)degrees, V = 2917.2(9 ) Angstrom(3), and Z = 2; 4c, orthorhombic, space group Pba2 with a = 22.65 7(2) Angstrom, b = 10.570(2) Angstrom, c = 10.664(3) Angstrom, alpha = beta = gamma = 90 degrees, V = 2554(1) Angstrom(3), and Z = 2; 6, triclinic, sp ace group P (1) over bar with a = 7.4667(8) Angstrom, b = 11.3406(12) Angst rom, c = 13.5470(14) Angstrom, alpha = 108.000(2)degrees, beta = 105.746(2) degrees, gamma = 94.300(2)degrees, V = 1033.8(2) Angstrom(3), and Z = 2.