Changes in thiamin, riboflavin, niacin, beta-carotene, vitamins C, A, D and E status of French elderly subjects during the first year of institutionalization

Vitamin status was assessed in 26 recently institutionalized elderly subjec ts by combining dietary and biochemical measurements of thiamin, fiboflavin , niacin, beta-carotene, vitamins C, A, D and E at admission (PI). and 1.5 (P2), 3.0 (P3), 4.5 (P4), 6.0 (P5), 12 (P6) months Later. I: At admission, except for vitamin A, mean vitamin intakes were lower than th e 1992 French Recommended Dietary Allowance. Thiamin, vitamins C, A, and E status seemed nearly satisfactory as less than one-fourth of the population sample had blood values lower than the cut-off point for thiamin (erythroc yte thiamin pyrophosphate < 0.17 mu mol/l), vitamin A (serum retinol < 1.05 mu mol/l), vitamin C (serum vitamin C < 11.3 mu mol/l) and vitamin E (seru m alpha-tocopherol < 9.3 mu mol/l) or higher than the cut-off point for thi amin (erythrocyte transketolase activity coefficient > 1.19). Almost half o f the subjects: for riboflavin and almost ail non supplemented subjects for vitamin D were in risk of vitamin deficiency (46%: had:an erythrocyte glut athione reductase activity coefficient > 1.19 and 72% had a plasma 25(OH)D- 3 < 25 nmol). During the study, vitamins status remained unchanged for ribo flavin, niacin, vitamins A, D and E, improved for vitamin C (P = 0.004) or impaired for thiamin (P = 0.008). Thus, institutionalization seemed to have no effect on riboflavin, niacin, vitamins A.,P and E. status and a slight effect on thiamin and vitamin C St atus.