Optimization of orthotopic colonic bladder: Implantation of tubularized mucosal flap from colonic segment into demucosalized urethra

If the urethral mucosa of a female could be replaced by another mucosa, one could augment the indication for orthotopic reconstruction of the bladder. A mucosal replacement technique for the female urethra is reported. A colo nic mucosal flap formed from a colonic bladder was used in a patient with b ladder cancer for whom cystectomy was indicated. For 3 years after the surg ery, the patient has maintained satisfactory voiding and urethral function. There has been no evidence of a recurrence. The orthotopic bladder with th e mucosal replacement technique can be applied to female patients who have a bladder cancer with a high risk of urethral recurrence.