Efficacy of oral adsorbent for treatment of peristomal fistula associated with Crohn's disease

Perianal fistulae are frequently seen complications in Crohn's disease. Alt hough surgical procedures such as Seton's method have been devised, many pa tients still suffer from fistulae that are resistant to conventional therap y. We administreved oral adsorbent to a patient with disease Crohn's who ha d a complicated peristomal fistula that did nor improve with conventional t herapy. Six grams of oral adsorbent (AST-120) were added daily to a regimen of elemental diet therapy and prednisolone. The fistula gradually decrease d in size after the administration of the oral adsorbent, and had healed co mpletely after 40 days' treatment. There were no side effects from the oral adsorbent. This case report suggests that oral adsorbent is an effective t reatment for peristomal fistula associated with Crohn's disease.