Idiopathic intracranial hypertension - A case report with optic nerve histopathology

We present the clinical and pathologic findings in an atypical case of idio pathic intracranial hypertension. A 51-year-old man had headaches, visual d eterioration, papilloedema, and deafness, Neuroimaging was normal, and cere brospinal fluid pressure monitoring confirmed increased intracranial pressu re. The patient was treated with a ventriculo-peritoneal shunt. Histopathol ogy revealed grossly atrophic optic nerves with almost complete axonal loss . The prelaminar portion of the optic nerves was thickened by gliosis and h yalinized capillaries, which have not been described previously.