Synthesis of C-C-bridged bis-isoflavones

Authors
Al-Maharik, N Kaltia, SAA Mutikainen, I Wahala, K
Citation
N. Al-maharik et al., Synthesis of C-C-bridged bis-isoflavones, J ORG CHEM, 65(8), 2000, pp. 2305-2308
Citations number
23
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
JOURNAL OF ORGANIC CHEMISTRY
ISSN journal
00223263 → ACNP
Volume
65
Issue
8
Year of publication
2000
Pages
2305 - 2308
Database
ISI
SICI code
0022-3263(20000421)65:8<2305:SOCB>2.0.ZU;2-W
Abstract
Unique C-C-bridged bis-isoflavones 5, 8, and 9 were obtained by reaction of 2-bromomethyl-7,4'-dimethoxyisoflavone 4 with ethyl cyanoacetate anion or tetraethylammonium cyanide or by Pd-catalyzed ethoxycarbonylation, respecti vely. The phenolic carboxylic acid 7 is available from 5 in two steps.